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Loef, M., Paepke, D., & Walach, H. (2023). Quality of Life in Breast Cancer Patients Treated With Mistletoe Extracts: A Systematic Review and Meta-Analysis. Integrative Cancer Therapies, 22, 15347354231198074.


Schad F, Thronicke A. Safety of Combined Targeted and Helixor® Viscum album L. Therapy in Breast and Gynecological Cancer Patients, a Real-World Data Study. International Journal of Environmental Research and Public Health 2023;20:2565. DOI: 20032565.


Kröz, M., Quittel, F., Reif, M. et al. Four-year follow-up on fatigue and sleep quality of a three-armed partly randomized controlled study in breast cancer survivors with cancer-related fatigue. Sci Rep 13, 2705 (2023).


Zerm R, Müller-Glinz A, Pranga D, Reif M, Bartsch C, Heckmann C, Gutenbrunner C, Kröz M. Influence of multimodal treatment on rest/activity and autonomic regulation in breast cancer patients with cancer related fatigue - results of a tri-center trial with a comprehensive cohort design, Complement Med Res. (2022).


Oei SL, Thronicke A, Matthes H, Schad F. Evaluation of the effects of integrative non-pharmacological interventions on the internal coherence and resilience of breast cancer patients. Support Care Cancer. 2021;29(3):1413-21. DOI: 10.1007/s00520-020-05617-4.


Schad F, Thronicke A, von Trott P, Oei SL: Analysis of changes in cancer-related fatigue of breast cancer patients receiving an integrative medicine program. Integrative Cancer Therapies 2020, 19. 12 pp. DOI: 10.1177/1534735420963780.


Ostermann T, Appelbaum S, Poier D, Boehm K, Raak C and Büssing A. A Systematic Review and Meta-Analysis on the Survival of Cancer Patients Treated with a Fermented Viscum album L. Extract (Iscador): An Update of Findings. Complement Med Res. 2020 Jan 10:1-12. doi: 10.1159/000505202.

Kts. lisätietoja julkaisijan sivuilta

Mehl A, Reif M, Zerm R, Pranga D, Friemel D, Berger B, Brinkhaus B, Gutenbrunner C, Büssing A and Kröz M: Impact of a Multimodal and Combination Therapy on Self-Regulation and Internal Coherence in German Breast Cancer Survivors With Chronic Cancer-Related Fatigue: A Mixed-Method Comprehensive Cohort Design Study. Integr Cancer Ther 2020; 19:1534735420935618. doi: 10.1177/1534735420935618


Oei SL, Thronicke A, Matthes H & Schad F. Evaluation of the effects of integrative non-pharmacological interventions on the internal coherence and resilience of breast cancer patients [published online ahead of print, 2020 Jul 15]. Support Care Cancer. 2020;10.1007/s00520-020-05617-4. doi: 10.1007/s00520-020-05617-4


Kröz M, Mehl A, Didwiszus A, Gelin-Kröz B, Reif M, Berger B, ten Brink F, Zerm R, Girke M, Gutenbrunner C and Büssing A. Reliability and first validity of the inner correspondence questionnaire for painting therapy (ICPTh) in a sample of breast cancer patients. Complementary Therapies in Medicine. 2019;42:355-360.

Oei SL, Thronicke A, Kröz M, Herbstreit C and Schad F. Supportive effect of Viscum album L. extracts on the sense of coherence in non-metastasized breast cancer patients. European Journal of Integrative Medicine. 2019;27:97-104.

Poier D, Bussing A, Rodrigues Recchia D, Beerenbrock Y, Reif M, Nikolaou A, Zerm R, Gutenbrunner C and Kröz M. Influence of a Multimodal and Multimodal-Aerobic Therapy Concept on Health-Related Quality of Life in Breast Cancer Survivors. Integr Cancer Ther. 2019;18:1534735418820447.

Drozdoff L, Klein E, Kalder M, Brambs C, Kiechle M, Paepke D. Potential interactions of biologically based complementary medicine in gynecological oncology. Integrative Cancer Therapies 2019: 18(10) pp. DOI: 10.1177/1534735419846392.

Pelzer F, Tröger W and Nat D R. Complementary Treatment with Mistletoe Extracts During Chemotherapy: Safety, Neutropenia, Fever, and Quality of Life Assessed in a Randomized Study. J Altern Complement Med, 2018;24:954-961. DOI: 10.1089/acm.2018.0159


Schad F, Thronicke A, Merkle A, Steele M, Kröz M, Herbstreit C and Matthes H. Implementation of an integrative oncological concept in daily care of a German certified Breast Cancer Centre. Complement Med Res 2018;25:85-91 

Oei SL, Thronicke A, Kröz M, Herbstreit C and Schad F. The Internal Coherence of Breast Cancer Patients Is Associated with the Decision-Making for Chemotherapy and Viscum album L. Treatment. Evid Based Complement Alternat Med 2018;2018:1065271 

Fritz P, Dippon J, Müller S, Goletz S, Trautmann C, Pappas X, Ott G, Brauch H, Schwab M, Winter S, Mürdter T, Brinkmann F, Faisst S, Rössle S, Gerteis A, Friedel G. Is mistletoe treatment beneficial in invasive breast cancer? A new approach to an unresolved problem. Anticancer Research 2018;38:1585-1593. DOI: 10.21873/anticanres.12388

Oei SL, Thronicke A, Kröz M, Herbstreit C and Schad F. Supportive Effect of Viscum album L. extracts on the inner feeling of Warmth in Non-metastasized Breast Cancer Patients. European Journal of Integrative Medicine 2017;27:97-104

Tröger W, Zdrale Z and Stankovic N. Fünf-Jahres-Nachbeobachtung von Patientinnen mit Brustkrebs nach einer randomisierten Studie mit Viscum album (L.) Extrakt. Deutsche Zeitschrift für Onkologie, 2016;48:105-110. DOI: 10.1055/s-0042-113505

Witt CM and Cardoso MJ. Complementary and integrative medicine for breast cancer patients - Evidence based practical recommendations. The Breast 2016;28:37-44

Tröger W, Zdrale Z, Tisma N and Matijasevic M. Additional Therapy with a Mistletoe Product during Adjuvant Chemotherapy of Breast Cancer Patients Improves Quality of Life: An Open Randomized Clinical Pilot Trial. Evidence-Based Complementary and Alternative Medicine, 2014;2014:01. Sep. DOI: 10.1155/2014/430518

Greenlee H, MJ DuPont-Reyes, LG Balneaves, LE Carlson, MR Cohen, G Deng, JA Johnson, M Mumber, D Seely, SM Zick, LM Boyce and D Tripathy: Clinical practice guidelines on the evidence-based use of integrative therapies during and after breast cancer treatment. CA Cancer J Clin. 2017; 67: 194-232 

Greenlee H, LG Balneaves, LE Carlson, M Cohen, G Deng, D Hershman, M Mumber, J Perlmutter, D Seely, A Sen, SM Zick, D Tripathy and O Society for Integrative: Clinical practice guidelines on the use of integrative therapies as supportive care in patients treated for breast cancer. J Natl Cancer Inst Monogr. 2014; 2014: 346-358 

Tröger W, Zdrale Z, Stankovic N and Matijasevic M. Five-year follow-up of patients with early stage breast cancer after a randomized study comparing additional treatment with viscum album (L.) extract to chemotherapy alone. Breast Cancer (Auckl), 2012;6:173-180. DOI: 10.4137/BCBCR.S10558

Eisenbraun J, Scheer R, Kroz M, Schad F and Huber R. Quality of life in breast cancer patients during chemotherapy and concurrent therapy with a mistletoe extract. Phytomedicine, 2011;18:151-157. DOI: 10.1016/j.phymed.2010.06.013

Wode K, Schneider T, Lundberg I and Kienle G S. Mistletoe treatment in cancer-related fatigue: a case report. Cases J, 2009;2:77. DOI: 10.1186/1757-1626-2-77

Tröger W, Jezdic S, Zdrale Z, Tisma N, Hamre H J and Matijasevic M. Quality of life and neutropenia in patients with early stage breast cancer: a randomized pilot study comparing additional treatment with mistletoe extract to chemotherapy alone. Breast Cancer 2009;3:35-45.

Loewe-Mesch A, Kuehn J J, Borho K, Abel U, Bauer C, Gerhard I, Schneeweiss A, Sohn C, Strowitzki T and v Hagens C. [Adjuvant simultaneous mistletoe chemotherapy in breast cancer--influence on immunological parameters, quality of life and tolerability]. Forsch Komplementmed, 2008;15:22-30. DOI: 10.1159/000112860


Beuth J, Schneider B and Schierholz J M. Impact of complementary treatment of breast cancer patients with standardized mistletoe extract during aftercare: a controlled multicenter comparative epidemiological cohort study. Anticancer Res, 2008;28:523-527

Grossarth-Maticek R, Ziegler R. Randomised and non-randomised prospective controlled cohort studies in matched-pair design for the long-term therapy of breast cancer patients with a mistletoe preparation (Iscador): a reanalysis.

Eur J Med Res. 2006 Nov; 11(11): 485–95.

Grossarth-Maticek R and Ziegler R. Prospective Controlled Cohort Studies on Long-Term Therapy of Breast Cancer Patients with a Mistletoe Preparation (Iscador®). Forschende Komplementärmedizin, 2006;13:285-292. DOI: 10.1159/000095378.

Auerbach L, Dostal V, Vaclavik-Fleck I, Kubista E, Rosenberger A, Rieger S, Tröger W and Schierholz J M. Signifikant höherer Anteil aktivierter NKZellen durch additive Misteltherapie bei chemotherapierten Mamma-Ca-Patientinnen in einer prospektiv-randomisierten doppelblinden Studie [Significant Higher Level of Activated NK-Cells in Patients with Breast Cancer Receiving Viscurn alburn Extract] during Chemotherapy. In: Scheer R, Bauer H. Becker R et al. Fortschritte  in der Misteltherapie. Stand der Forschung und klinischen Anwendung. Essen, KVC Verlag, 2005. S.543-554.

von Hagens C, A Loewe-Mesch, JJ Kuehn, U Abel and I Gerhard (2005). Prospektive kontrollierte nicht randomisierte Machbarkeits-Studie zu einer postoperativen simultanen Mistel-/Chemotherapie bei Patientinnen mit Mammakarzinom - Ergebnisse zu Rekrutierbarkeit, Immunparametern, Lebensqualität und Verträglichkeit. In: Scheer R, Bauer H. Becker R et al. Fortschritte  in der Misteltherapie. Stand der Forschung und klinischen Anwendung. Essen, KVC Verlag, 2005. S. 567-578.

Piao B K, Wang Y X, Xie G R, Mannsmann U, Matthes H, Beuth J and Lin H S. Impact of complementary mistletoe extract treatment on quality of life in breast, ovarian and non-small cell lung cancer patients. A prospective randomized controlled clinical trial. Anticancer Research 2004;24:303-310

Bock P R, Friedel W E, Hanisch J, Karasmann M and Schneider B. [Efficacy and safety of long-term complementary treatment with standardized European mistletoe extract (Viscum album L.) in addition to the conventional adjuvant oncologic therapy in patients with primary non-metastasized mammary carcinoma. Results of a multi-center, comparative, epidemiological cohort study in Germany and Switzerland]. Arzneimittelforschung, 2004;54:456-466. DOI: 10.1055/s-0031-1296999

Grossarth-Maticek R, Kiene H, Baumgartner SM, Ziegler R. Use of Iscador, an extract of European mistletoe (Viscum album), in cancer treatment: prospective nonrandomized and randomized matched-pair studies nested

within a cohort study. Altern Ther Health Med. 2001 May-Jun; 7(3): 57–66.

Hoffmann J, Hajto T. Iscadorbehandlung beim metastasierenden Mammakarzinom. Krebsgeschehen. 1982;(3): 71–5.

Leroi R. Nachbehandlung des operierten Mammakarzinoms mit Viscum album. Helv Chir Acta. 1977 Jun; 44(3): 403–14.

Leroi R. Malignomtherapie mit neuen Iscador-Praparaten. Krebsgeschehen. 1975; 7(5):124–6.

Günzler M, Salzer G. Iscadortherapie in derNachbehandlung operierter Carcinome. Österr Ärzteztg. 1969; 24(20): 2290–4.

Majewski A, Bentele W. Uber Zusatzbehandlung beim weiblichen Genitalkarzinom. Zentralbl Gynakol. 1963; 85(20): 696–700.



Biegel U, Stratmann N, Knauf Y, Ruess K, Reif M, Wehrend A. Postoperative adjuvante Therapie mit einem Mistelextrakt (Viscum album ssp. album) bei Hündinnen mit Mammatumoren. Complementary Medicine Research 2017;24(3):349-357. DOI: 10.1159/000485228

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