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Mistelihoidon näyttö kliinisissä tutkimuksissa

Positiivinen yhteisvaikutus (synergia) muiden onkologisten hoitojen kanssa

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Wode, K., Kienle, G. S., Björ, O., Fransson, P., Sharp, L., Elander, N. O., Bernhardson, B.-M., Johansson, B., Ardnor, C. E., Scheibling, U., Nordberg, J. H., & Henriksson, R. (2024). Mistletoe Extract in Patients With Advanced Pancreatic Cancer. Dtsch Arztebl International, 121(11), 347-354. https://www.aerzteblatt.de/int/article.asp?id=239558 
 

Shin, J., Yim, E., & Kang, C. M. (2023). Viscum album, as alternative and bridge to palliative chemotherapy in recurrent gallbladder cancer following laparoscopic radical cholecystectomy: a case report. Korean J Clin Oncol, 19(2), 88-92. https://doi.org/10.14216/kjco.23016 

 

Thronicke A, Reinhold T, von Trott P, Grah C, Matthes B, Matthes H & Schad F. Cost-effectiveness of real-world administration of chemotherapy and add-on Viscum album L. therapy compared to chemotherapy in the treatment of stage IV NSCLC patients. Plos ONE. 2020;15(7):e0236426. Published 2020 Jul 27. doi: 10.1371/journal.pone.0236426

 

Thronicke A, Reinhold T, von Trott P, Matthes H & Schad F. Cost-Effectiveness of Real-World Administration of Concomitant Viscum album L. Therapy for the Treatment of Stage IV Pancreatic Cancer. Evid Based Complement Alternat Med. 2020;2020:3543568. Published 2020 Mar 12. doi: 10.1155/2020/3543568

 

Weissenstein U, Kunz M, Oufir M, Wang J T, Hamburger M, Urech K, Regueiro U and Baumgartner S. Absence of herb-drug interactions of mistletoe with the tamoxifen metabolite (E/Z)-endoxifen and cytochrome P450 3A4/5 and 2D6 in vitro. BMC Complement Altern Med, 2019;19:23. DOI: 10.1186/s12906-019-2439-2

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Thronicke A, Oei S L, Merkle A, H M and Schad F. Clinical Safety of Combined Targeted and Viscum album L. Therapy in Oncological Patients. Medicines (Basel), 2018;5:100. DOI: 10.3390/medicines5030100

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Thronicke A, Oei SL, Grah C, Matthes B and Schad F. Nivolumab-induced toxicity profile in patients with advanced or metastasized lung cancer treated with Viscum album L. extracts. In Proceedings of the German Cancer Congress, DKK2018, 2018.

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Schad F, Thronicke A, Steele ML, Merkle A, Matthes B, Grah C and Matthes H. Overall survival of stage IV non-small cell lung cancer patients treated with Viscum album L. in addition to chemotherapy, a real-world observational multicenter analysis. PLoS One, 2018;13:e0203058. DOI: 10.1371/journal.pone.0203058

 

Schad F, Axtner J, Kroz M, Matthes H and Steele ML. Safety of Combined Treatment With Monoclonal Antibodies and Viscum album L Preparations. Integr Cancer Ther, 2018;17:41-51. DOI: 10.1177/1534735416681641

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Weissenstein U, Kunz M, Urech K, Regueiro U and Baumgartner S. Interaction of a standardized mistletoe (Viscum album) preparation with antitumor effects of Trastuzumab in vitro. BMC Complement Altern Med, 2016;16:271. DOI: 10.1186/s12906-016-1246-2

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Tröger W, Zdrale Z and Stankovic N. Fünf-Jahres-Nachbeobachtung von Patientinnen mit Brustkrebs nach einer randomisierten Studie mit Viscum album (L.) Extrakt. Deutsche Zeitschrift für Onkologie, 2016;48:105-110. DOI: 10.1055/s-0042-113505

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Evans M, Bryant S, Huntley AL and Feder G. Cancer patients' experiences of using mistletoe (Viscum album): a qualitative systematic review and synthesis. The Journal of Alternative and Complementary Medicine (New York, N.Y.) 2016;22(2):134–144.​

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Weissenstein U, Kunz M, Urech K and Baumgartner S. Interaction of standardized mistletoe (Viscum album) extracts with chemotherapeutic drugs regarding cytostatic and cytotoxic effects in vitro. BMC Complementary and Alternative Medicine, 2014;14:01. Sep. DOI: 10.1186/1472-6882-14-6

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Tröger W, Zdrale Z, Tisma N and Matijasevic M. Additional Therapy with a Mistletoe Product during Adjuvant Chemotherapy of Breast Cancer Patients Improves Quality of Life: An Open Randomized Clinical Pilot Trial. Evidence-Based Complementary and Alternative Medicine, 2014;2014:01. Sep. DOI: 10.1155/2014/430518

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Bar-Sela G, Wollner M, Hammer L, Agbarya A, Dudnik E and Haim N. Mistletoe as complementary treatment in patients with advanced non-small-cell lung cancer treated with carboplatin-based combinations: a randomised phase II study. Eur J Cancer, 2013;49:1058-1064 DOI: 10.1016/j.ejca.2012.11.007.

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Tröger W, Zdrale Z, Stankovic N and Matijasevic M. Five-year follow-up of patients with early stage breast cancer after a randomized study comparing additional treatment with viscum album (L.) extract to chemotherapy alone. Breast Cancer (Auckl), 2012;6:173-180. DOI: 10.4137/BCBCR.S10558

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Matthes H, Friedel WE, Bock PR and Zänker KS. Molecular mistletoe therapy: friend or foe in established anti-tumor protocols? A multicenter, controlled, retrospective pharmaco-epidemiological study in pancreas cancer. Curr Mol Med, 2010;10:430-439. DOI: 10.2174/156652410791317057

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Kienle GS and Kiene H. Review article: Influence of Viscum album L (European mistletoe) extracts on quality of life in cancer patients: a systematic review of controlled clinical studies. Integr Cancer Ther, 2010;9:142-157. DOI: 10.1177/1534735410369673

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Tröger W, Jezdic S, Zdrale Z, Tisma N, Hamre HJ and Matijasevic M. Quality of life and neutropenia in patients with early stage breast cancer: a randomized pilot study comparing additional treatment with mistletoe extract to chemotherapy alone. Breast Cancer, 2009;16:35-45

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Friedel WE, Matthes H, Bock PR and Zänker KS. Systematic evaluation of the clinical effects of supportive mistletoe treatment within chemo- and/or radiotherapy protocols and long-term mistletoe application in nonmetastatic colorectal carcinoma: multicenter, controlled, observational cohort study. J Soc Integr Oncol 2009;7:137-145

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Piao BK, Wang YX, Xie GR, Mansmann U, Matthes H, Beuth J and Lin HS. Impact of complementary mistletoe extract treatment on quality of life in breast, ovarian and non-small cell lung cancer patients. A prospective randomized controlled clinical trial. Anticancer Res, 2004;24:303-309.

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Bock PR, Friedel WE, Hanisch J, Karasmann M and Schneider B. [Efficacy and safety of long-term complementary treatment with standardized European mistletoe extract (Viscum album L.) in addition to the conventional adjuvant oncologic therapy in patients with primary non-metastasized mammary carcinoma. Results of a multi-center, comparative, epidemiological cohort study in Germany and Switzerland]. Arzneimittelforschung, 2004;54:456-466. DOI: 10.1055/s-0031-1296999

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